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Recent Publications

Complete publication list can be found at:

  • Fakih R, Goldstein RH, Kozlov G, Gehring K. Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver​. J Biol Chem. 2023 Feb 22;299(4):103055. PMID: 36822330.

  • Fakih R, Sauvé V, Gehring K. Feedforward activation of PRKN/parkin. Autophagy. 2022 Jul 15:1-2.  PMID: 35838500.

  • Sauvé V, Sung G, MacDougall EJ, Kozlov G, Saran A, Fakih R, Fon EA, Gehring K. Structural basis for feedforward control in the PINK1/Parkin pathway. EMBO J. 2022 Jun 14;41(12):e109460. PMID: 35491809.

  • Fakih R, Sauvé V, Gehring K. Structure of the second phosphoubiquitin-binding site in parkin. J Biol Chem. 2022 Jul;298(7):102114.  PMID: 35690145.

  • Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ, Maraia RJ, Gehring K. Structural basis of 3'-end poly(A) RNA recognition by LARP1. Nucleic Acids Res. 2022 Aug 18:gkac696. PMID: 35979957.

  • Vranas M, Lu Y, Rasool S, Croteau N, Krett JD, Sauvé V, Gehring K, Fon EA, Durcan TM, Trempe JF. Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria. Open Biol. 2022 Jan;12(1):210255. PMID: 35042405.

  • Kaisari S, Miniowitz-Shemtov S, Sitry-Shevah D, Shomer P, Kozlov G, Gehring K, Hershko A. Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2121478119. PMID: 35217622.

  • Gehring K, Kozlov G, Yang M, Fakih R. The double lives of phosphatases of regenerating liver: A structural view of their catalytic and noncatalytic activities. J Biol Chem. 2022 Jan;298(1):101471. PMID: 34890645.

  • Mattijssen S, Kozlov G, Fonseca BD, Gehring K, Maraia RJ. LARP1 and LARP4: up close with PABP for mRNA 3' poly(A) protection and stabilization. RNA Biol. 2021 Feb;18(2):259-274. PMID: 33522422.

  • Chen YS, Kozlov G, Moeller BE, Rohaim A, Fakih R, Roux B, Burke JE, Gehring K. Crystal structure of an archaeal CorB magnesium transporter. Nat Commun. 2021 Jun 29;12(1):4028. PMID: 34188059.

  • Gehring K, Miki H. Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity. Br J Cancer. 2021 Mar;124(6):1035-1036. PMID: 33268817.

  • Mattijssen S, Kozlov G, Gaidamakov S, Ranjan A, Fonseca BD, Gehring K, Maraia RJ. The isolated La-module of LARP1 mediates 3' poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1. RNA Biol. 2021 Feb;18(2):275-289. PMID: 33292040.

  • Gehring K, Kozlov G, Yang M, Fakih R. The double lives of phosphatases of regenerating liver: A structural view of their catalytic and noncatalytic activities. J Biol Chem. 2022 Jan;298(1):101471. PMID: 34890645.

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